Soho or SoHo is one of Manhattan’s district bounded by Houston St on the north, Lafayette St on the east, Canal St on the south, and Varick St on the west. Soho is an acronym for South of Houston (pronounced HOUSE-tin) St, without relation to the Soho district of London, England. Its name has been the model for other new district descriptions in New York City ... More> e.g. TriBeCa and DUMBO. It is famous for the galleries and shops lining its narrow streets and Little Italy is packed with New York’s best Italian restaurants and cafes. The SoHo’s major sights are such as the Alternative Museum Broadway & West Houston Street, New Museum of Contemporary Art Broadway, while Greenwich Village is nearby, features lots of Arts places.